What liquid should be given for gout attack: Analysis of hot topics on the Internet in the past 10 days
Recently, topics related to gout treatment have aroused heated discussions on major health forums and social media, especially regarding infusion treatment options during acute attacks. This article will combine the hot topics on the Internet in the past 10 days to conduct a structured analysis of infusion selection and precautions during gout attacks.
1. Popularity statistics of gout-related topics across the entire network (last 10 days)
| Platform | Topic keywords | amount of discussion |
|---|---|---|
| #Gout first aid method# | 128,000 | |
| Zhihu | "Precautions for Gout Infusion" | 3400+ answers |
| Douyin | Gout infusion treatment | 56 million views |
| Station B | Gout emergency room record | The number of comments is 21,000 |
2. Commonly used infusion regimens for acute gout attacks
| drug type | Representative medicine | Mechanism of action | Frequency of use |
|---|---|---|---|
| NSAIDs | flurbiprofen axetil | Inhibit prostaglandin synthesis | Clinical first choice (68%) |
| Glucocorticoids | Methylprednisolone | anti-inflammatory immunosuppression | Second choice (22%) |
| alkaline solution | sodium bicarbonate | alkalize urine | Adjuvant therapy (45%) |
3. Key points of expert consensus (latest in 2024)
1.The golden 24-hour rule:Infusion treatment has the best effect if started within 24 hours after the attack, and the pain relief time can be shortened by 40-50%.
2.Individualized plan:It needs to be adjusted according to the patient's renal function, comorbid diseases, etc. Patients with renal insufficiency need to avoid using NSAIDs.
3.Contraindications for combined use:It is prohibited to combine colchicine with macrolide antibiotics such as clarithromycin as it may cause serious adverse reactions.
4. The 5 issues that netizens are most concerned about
| Ranking | question | frequency of occurrence |
|---|---|---|
| 1 | How long do the effects of infusion therapy last? | 12800+ |
| 2 | How long after the infusion can I drink alcohol? | 9760+ |
| 3 | How much does infusion therapy cost? | 8540+ |
| 4 | Which one works faster, infusion or oral medicine? | 7320+ |
| 5 | What situations require infusion therapy? | 6810+ |
5. Things to note
1.Fluid volume control:It is recommended that the daily infusion volume be controlled at 2000-3000ml. Excessive infusion may increase the burden on the heart.
2.Monitoring indicators:During treatment, blood uric acid (target <360 μmol/L), creatinine and urine pH (ideal value 6.2-6.9) need to be monitored regularly.
3.Diet coordination:During the infusion period, the intake of high-purine foods should be strictly limited, and the total daily purine intake should be <150 mg.
6. Latest treatment trends
According to recent academic conference disclosures,New urate oxidase drugsThe intravenous preparation has entered Phase III clinical trials and is expected to be launched in the next 2 years. The drug can directly catalyze the decomposition of uric acid and has breakthrough therapeutic significance for patients with refractory gout.
The statistical period of the data in this article is from March 10 to March 20, 2024, and combines public information from the official websites of 30 medical institutions, 5 major social platforms, and 3 professional medical databases. The actual treatment plan is subject to the diagnosis of a licensed physician.
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